| Main Title |
Ames Salmonella/mammalian Microsome Mutagenicity Test and Reverse Mutation Assay - E. Coli Wp2 Uvra a (Standard Plate Test and Preincubation Test) (Oct. 19, 1988) W-letter 12/16/1991. |
| CORP Author |
BASF A.G., Limburgerhof (Germany, F.R.). Agricultural Research Station.; BASF Corp., Mount Olive, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1991 |
| Report Number |
86-920000590 |
| Stock Number |
OTS0535474 |
| Additional Subjects |
Toxicology ;
Health effects ;
4-methylbenzaldehyde (104-87-0) ;
Genotoxicity ;
Gene Mutations ;
Bacteria ;
In Vitro ;
Toxic substances ;
Laboratory animals ;
CAS No 104-87-0
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0535474 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
32p |
| Abstract |
P-Tolualdehyde (CAS No. 104-87-0) was evaluated for mutagenicity in the Ames test (strains TA1535, TA100, TA1537, TA98) with and without metabolic activation (S-9 mix) and in the Escherichia coli (WP2 uvrA) reverse mutation assay at a dose range of 20 ug - 5000 ug/plate in the standard plate test (SPT) and 4 ug - 2500 ug/plate in the preincubation test (PIT). No bacteriotoxic effect was observed with E. coli. Bacteriotoxicity was detected in all Salmonella strains detected at 2500 ug/plate (PIT) and at 5000 ug/plate (SPT). The test substance was determined to be non- mutagenetic. |
