Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Summary of the U.S. EPA Workshop on the Relationship between Exposure Duration and Toxicity
CORP Author Eastern Research Group, Inc., Lexington, MA.;Environmental Protection Agency, Washington, DC. National Center for Environmental Assessment.
Publisher U.S. Environmental Protection Agency,
Year Published 1998
Report Number EPA 600/R-99/081; EPA-68-D5-0028; NCEA-W-0647
Stock Number PB2001-103490
OCLC Number 43101717
Subjects Toxicology--Dose-response relationship--Congresses ; Health risk assessment--Congresses
Additional Subjects Toxicity ; Risk assessments ; Intermittent ; Bursts ; Spikes ; Modeling ; Workshops ; Exposure duration ; Dose-duration relationships
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
ELBD  EPA 600-R-99-081 AWBERC Library/Cincinnati,OH 01/14/2000
NTIS  PB2001-103490 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 1 v. (various pagings) : ill.; 28 cm.
Current risk assessment procedures are typically based on overall daily exposure levels, and tend to emphasize effects resulting from continuous exposure over a lifetime. However, scientists now realize that exposures are more likely to be experienced as bursts or spikes, or intermittent exposures of varying levels. The U.S. Environmental Protection Agency's Risk Assessment Forum is beginning to examine how dose-duration relationships are or can be incorporated into the risk assessment process for less-than-lifetime exposures. As part of this effort, the Forum, together with the Harvard School of Public Health, held a workshop August 5 and 6, 1998, to discuss the current understanding of dose-duration relationships, the approaches that can be used in their modeling, the inclusion of these relationships in risk assessment, and future directions in this area. The workshop provided a forum for open discussion and identifying areas of consensus, as well as areas of difference.
"September 30, 1998." "Contract no. 68-D5-0028, work assignment no. 98-10." Includes bibliographical references.