Recorded at the Howard Hughes Medical Institute, Dec. 2008.

Eric R. Kandel and Thomas M. Jessell, two leading neuroscientists, discuss current understanding of memory and brain development. Disc 1. Lecture 1. Mapping memory in the brain. Lecture 2. Building brains: the molecular logic of nueral circuits. Lecture 3. Plan of action: how the spinal cord controls movement. Lecture 3. Memories are made of this -- Special features: Controlling animal locomotion ; Electrical activity of neurons ; Visualizing learning ; Spatial-learning maze -- Animations: Molecular mechanism of synaptic function ; Development of the human embryonic brain ; Signal molecules trigger transcription factors ; Repellent ephrin signals guide limb innervations ; Molecular activity in Aplysia memory ; Molecular basis of mouse memory -- Video clips: Clive Wearing, a man without a memory ; A patient with conduction aphasia ; Growth cones in action ; Charles Freed, a man without proprioception ; Muscle activity during walking and hopping ; Ian Waterman: Visual compensation for proprioception loss ; Using spatial memory to negotiae an obstacle ; Aplsia's gill-withdrawal reflex and sensitization ; Mice demonstrate spatial memory in a maze -- Disc 2. Interviews and discussion session.