Record Display for the EPA National Library Catalog


Main Title Fluoride: Dose-Response Analysis For Non-Cancer Effects. Fluoride-Related Skeletal Effects: Evaluations of Key Studies.
Author J. M. Donohue
CORP Author Oak Ridge National Lab., TN.; Environmental Protection Agency, Washington, DC. Health and Ecological Criteria Div.
Year Published 2008
Report Number EPA 820-R-10-017
Stock Number PB2011-104501
Additional Subjects Fluorides ; Dosage ; Drinking water ; Food ; Exposure ; Bones ; Analytical methods ; Biological effects ; Skeletal effects ; Public health ; Toxicology ; Statistical data ; Surveys
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
NTIS  PB2011-104501 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 72p
Prior to initiating the dose-response analysis for fluoride-related skeletal effects, the Office of Water (OW) critically evaluated the studies that had been cited and utilized by the National Research Council (NRC, 2006) in their report Fluoride in Drinking Water: A Scientific Review of EPAs Standards. Additional studies identified in the OW initial literature search (2006) were also evaluated. This document is a compilation of the study evaluations arranged alphabetically by the name of the lead author. Critical information fields examined and summarized include endpoint studied, type of study and population studied, exposure period and assessment, characterization of study groups, analytical methods and study design, parameters monitored, statistical methods employed, results (including critical tables and figures) authors conclusions, critical references and definitions, profilers appraisal, and critical review of the profilers assessment. Studies of fluoride-related skeletal effects identified and added to the dose-response analysis for the non-cancer effects document after its external peer review were not evaluated in this fashion.