Record Display for the EPA National Library Catalog


Main Title Pericyte of a Teleost Fish: Ultrastructure, Position, and Role in Neoplasia as Revealed by a Fish Model.
Author Couch, J. A. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL.
Publisher c1990
Year Published 1990
Report Number EPA/600/J-90/366;
Stock Number PB91-163808
Additional Subjects Fishes ; Neoplasms ; Cytology ; Blood vessels ; Electron microscopy ; Reprints ; Pericytes ; Cyprinodon variegatus
Library Call Number Additional Info Location Last
NTIS  PB91-163808 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 10p
The morphology and position of the pericyte, a periendothelial cell, is described for a teleost fish, Cyprinodon variegatus. The cell was found attached to the abluminal surfaces of capillaries, venules, and arterioles of the submucosa of the midgut of the fish. The cell was encompassed by a thin basal lamina, possessed numerous plasmalemmal vesicles, a sole region which contained thinner actin-like filaments and possibly thicker myosin-like filaments, and ranged in form from ovoid to stellate, with long cytoplasmic extensions that partially covered the endothelium of the associated microvessel. The pericyte of C. variegatus has been shown to give rise to hemangiopericytomas. The anatomical position, in relationship to microvasculature in the fish is very similar to other vertebrate pericytes. Limited evidence suggests that small fish species may be excellent study models for further elucidation of pericyte form, function, and role in disease.