| Main Title |
Plasma Binding of 1-Butanol, Phenol, Nitrobenzene and Pentachlorophenol in the Rainbow Trout and Rat: A Comparative Study. |
| Author |
Schmieder, P. K. ;
Henry, T. R. ;
|
| CORP Author |
Environmental Research Lab.-Duluth, MN. ;College of Saint Scholastica, Duluth, MN. |
| Publisher |
c1988 |
| Year Published |
1988 |
| Report Number |
EPA/600/J-88/374; |
| Stock Number |
PB90-103631 |
| Additional Subjects |
Blood proteins ;
Binding ;
Toxicology ;
Trout ;
Rats ;
Phenol ;
Butanol ;
Nitrobenzenes ;
Comparison ;
Reprints ;
Pharmacokinetics ;
Pentachlorophenol
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-103631 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
The in vitro binding of 1-butanol, phenol, nitrobenzene, and pentachlorophenol in trout plasma and rat plasma was determined. Binding to rainbow trout plasma proteins agreed within 9% of that observed in rat plasma. Percentage bound to rainbow trout (2-99%) or rat (10-99%) plasma proteins increased as the log octanol/water partition coefficient of the chemicals increased within the Log P 1-3 range, and was suggestive of hydrophobic interactions in binding. |
