GreenChill's mission in developing this document is to assist food retailers with an orderly, low cost transition option from HCFC-22 to a substitute chemical, and to provide food retailers with a set of best practices related to the conversion process and HCFC-22 reclamation. The purpose of this Best Practices Guideline is to provide food retailers with fact-based, neutral information on best practices for every aspect of the HCFC-22 conversion process: Reasons to consider retrofitting refrigeration equipment that uses HCFC-22; The HFC retrofit options currently available to food retailers; The factors that should be considered when assessing substitute chemicals; The current best practices for transitioning to HFC substitutes and improving leak tightness; Recovery techniques for HCFC-22; HCFC-22 disposal and reclamation options; and Case studies to provide you with real-life examples from retrofits in the field. Different sections of these Guidelines will be of value to various people within a food retail organization. The document is designed to assist a wide range of stakeholders in the food retail market including, but not limited to, strategic decision-makers, store managers, and technicians participating in the HCFC-22 conversion process. The scope of this document is limited to non-ozone-depleting, HFC substitutes for HCFC-22 in commercial refrigeration systems. Our goal is to include every non-ozone-depleting HFC substitute chemical that can potentially be used by food retailers in place of HCFC-22. The only limitations in terms of the scope of the chemicals we have included in the Guidelines are that the chemicals must be approved by the U.S. Environmental Protection Agency's Significant New Alternatives Policy Program (SNAP), and they must be non-ozone-depleting.