Record Display for the EPA National Library Catalog

RECORD NUMBER: 439 OF 896

Main Title Maternal Hepatic and Embryonic Effects of 1,2,4- Trichlorobenzene in the Rat.
Author Kitchin, K. T. ; Ebron, M. T. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA-600/J-83-135;
Stock Number PB84-144310
Additional Subjects Toxicology ; Liver ; Reproduction(Biology) ; Embryos ; Rats ; Laboratory animals ; Reprints ; Benzene/trichloro
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  PB84-144310 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 14p
Abstract
The possible maternal hepatic and reproductive effects of 1,2,4-trichlorobenzene (TCB) were assessed in rats given 0, 36, 120, 360, and 1200 mg/kg/day of TCB on Days 9-13 of gestation. The animals were sacrificed on Day 14 of pregnancy. Maternal deaths (2/9 rats 6/6 rats) were recorded in the 360 and 1200 mg/kg/day treatment groups and body weights gain was significantly decreased in the 360 mg/kg/day TCB group. Maternal liver weight liver/body weight ratio, and hepatic microsomal protein content were unaffected by TCB treatment.