Main Title |
Uptake, metabolism and disposition of xenobiotic chemicals in fish : Wisconsin power plant impact study / |
Author |
Lech, John J.
|
Other Authors |
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CORP Author |
Environmental Research Laboratory (Duluth, Minn.) |
Publisher |
Environmental Research Laboratory--Duluth, Office of Research and Development, U.S. Environmental Protection Agency ; Available to the public through the National Technical Information Service, |
Year Published |
1980 |
Report Number |
EPA-600/3-80-082; EPA-R-803971 |
Stock Number |
PB81-135329 |
OCLC Number |
06947294 |
Subjects |
Xenobiotics--Metabolism. ;
Fishes--Effect of water pollution on.
|
Additional Subjects |
Xenobiotic metabolism ;
Fishes, Effect of water pollution on ;
Water pollution ;
Toxicology ;
Organic compounds ;
Electric power plants ;
Industrial wastes ;
Toxicity ;
Cycloalkane hydrocarbons ;
Public health ;
Pesticides ;
Chlorine organic compounds ;
Aromatic polycyclic hydrocarbons ;
Water pollution effects(Animals) ;
Coal fired power plants ;
Toxic substances ;
Polychlorinated biphenyls ;
Naphthalene ;
Naphthalene/methyl ;
Phenol/pentachloro ;
Anisole/pentachloro ;
Benzene/trichloro
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EHAM |
SH174.L4 1980 |
|
Region 1 Library/Boston,MA |
04/29/2016 |
EJBD ARCHIVE |
EPA 600/3-80-082 |
|
Headquarters Library/Washington,DC |
04/17/2014 |
EJED |
EPA 600/3-80-082 |
|
OCSPP Chemical Library/Washington,DC |
01/01/1988 |
ELAD |
EPA 600-3-80-082 |
|
Region 5 Library/Chicago,IL |
04/29/2016 |
ELBD |
EPA 600-3-80-082 |
|
AWBERC Library/Cincinnati,OH |
09/13/2002 |
ELDD |
EPA-600/3-80-082 |
|
CCTE/GLTED Library/Duluth,MN |
06/04/1999 |
ESAD |
EPA 600-3-80-082 |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
NTIS |
PB81-135329 |
Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. |
|
01/01/1988 |
|
Collation |
xv, 141 pages : illustrations ; 28 cm. |
Abstract |
The effects and fate in fish of a number of chemicals, including hydrocarbons and chlorinated hydrocarbons, have been examined. The interactions between these chemicals and fish have been studied using several approaches. The uptake an elimination of 14C-labeled napthalene, 2-methylnapthalene, 1,2,4-trichlorobenzene, pentachlorophenol, and pentachloroanisole were studied. Each of these chemicals was taken up rapidly by rainbow trout. Increasing the duration of exposure to 14C-napthalene or 14C-2-methylnapthalene affected the elimination of 14C-containing components from these fish. Activities of cytochrome P-450-related xenobiotic metabolizing enzymes in rainbow trout livers were induced. The quantities of biliary metabolites in these fish were considerably higher than those found in non-induced trout. Piperonyl butoxide reduced levels of biliary metabolites of pentachloranisole and di-2-ethylhexyl-phthalate in trout and increased tissue levels of these chemicals. The high levels of biotransformation products of these chemicals found in fish bile during and after exposure to the chemicals in these studies support the possible use of bile sampling in pollutant-modelling programs. |
Notes |
"Study conducted in cooperation with Wisconsin Power and Light Company, Madison Gas and Electric Company, Wisconsin Public Service Corporation, Wisconsin Public Service Commission, and Wisconsin Department of Natural Resources." "August 1980." Includes bibliographical references (pages 131-140). "Grant no. R803971." |