Record Display for the EPA National Library CatalogRECORD NUMBER: 11 OF 22
|Main Title||Multigeneration Study of 1,2,4-Trichlorobenzene in Rats.|
|Author||Robinson, Kathy S. ; Kavlock, Robert J. ; Chernoff, Neil ; Gray, L. Earl ;|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC.|
|Additional Subjects||Potable water ; Water pollution ; Adrenal gland ; Rats ; Laboratory animals ; Concentration(Composition) ; Ingestion(Biology) ; Chlorine organic compounds ; Physiological effects ; Chlorobenzenes ; Reprints ; Benzene/trichloro|
Rats were continuously exposed to 0, 25, 100, or 400 ppm 1,2,4-trichlorobenzene (TCB) in the drinking water, beginning with birth of the Fo generation and continuing through weaning of the F2 generation. These studies demonstrate that chronic or acute doses of TCB can produce adrenal enlargement in rats.