||Evaluation of In Vitro Production of the Beta Chemokine, MCP-1, as a Diagnostic Test in diisocyante Asthma, with Cover Letter dated 03/03/1999.
||International Isocyanate Inst., Parsippany, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
In vitro ;
Industrial hygiene ;
CAS No 26471-62-5
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The primary aim of this proposal is to validate dlisocyanate (DIISO) specific in vitro cellular MCP-1 as a diagnostic marker of occupational asthma (OA) by using the specific bronchoprovocation test (SBPT) as the gold standard for diagnosis. A secondary aim of the study is to evaluate the sensitivity and specificity ofin vitro serum DIISO-HSA specific IgG and IgE responses for identification ofdiisocyanate asthma (DA) confirmed by the SBPT. This report summarizes and discusses the results obtained in this study.