The National Oceanic and Atmospheric Administration's Multi-Layer Model (NOAA-MLM) is used by several operational dry deposition networks for estimating the deposition velocity of O3, SO2, HNO3, and particles. The NOAA-MLM requires hourly values of meteorological variables and since collection of on-site meteorology can be expensive, a study was performed to evaluate NOAA-MLM predicted deposition velocities using modeled meteorological data in lieu of on-site data. NOAA-MLM was run for three sites in the Clean Air Status and Trends Network using on-site data as well as the output of two mesoscale meteorological models, Eta and MM5. Atmospheric turbulence and local precipitation proved particularly difficult to match between the on-site and modeled data. Some modifications to the NOAA-MLM and the manner in which the Eta and MM5 data are processed may improve the usefulness of these data as a surrogate for the on-site observation.