Record Display for the EPA National Library Catalog

RECORD NUMBER: 13 OF 64

Main Title Evolutionary Bioinformatics [electronic resource] /
Type EBOOK
Author Forsdyke, Donald R.
Publisher Springer US,
Year Published 2006
Call Number QH324.2-324.25
ISBN 9780387334196
Subjects Life sciences ; Human genetics ; Proteomics ; Bioinformatics ; Evolution (Biology) ; Animal genetics ; Statistics
Internet Access
Description Access URL
http://dx.doi.org/10.1007/978-0-387-33419-6
Collation XXII, 424p. 86 illus. online resource.
Notes
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Information and DNA -- Memory - A Phenomenon of Arrangement -- Chargaff's First Parity Rule -- Information Levels and Barriers -- Parity and Non-Parity -- Chargaff's Second Parity Rule -- Stems and Loops -- Chargaff's Cluster Rule -- Mutation and Speciation -- Species Survival and Arrival -- Chargaff's GC rule -- Conflict within Genomes -- Conflict Resolution -- Exons and Introns -- Complexity -- Conflict between Genomes -- Self/Not-Self? -- The Crowded Cytosol -- Sex and Error-Correction -- Rebooting the Genome -- The Fifth Letter -- Epilogue To Perceive is Not To Select. Evolutionary Bioinformatics aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with the exciting topics of gene discovery and database-searching, such books have hardly considered genomes as information channels through which multiple forms and levels of information have passed through the generations. This "new bioinformatics," contrasts with the "old" gene-based bioinformatics that so preoccupies previous texts. Evolutionary Bioinformatics extends a line of evolutionary thought that leads from the nineteenth century (Darwin, Butler, Romanes, Bateson), through the twentieth (Goldschmidt, White), and into the twenty first (the final works of the late Stephen Jay Gould). Long an area of controversy, diverging views may now be reconciled. The book is unique in emphasising non-genic aspects of bioinformatics, and linking modern evolutionary biology to a history that extends back to the nineteenth century. Forms of information that we are familiar with (mental, textual) are related to forms we are less familiar with (hereditary).