Record Display for the EPA National Library Catalog
RECORD NUMBER: 32 OF 36| Main Title | Respiratory Tract Dosimetry Model for Air Toxics (October 1990). | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Author | Overton, J. H. ; | |||||||||||
| CORP Author | Health Effects Research Lab., Research Triangle Park, NC. Inhalation Toxicology Div. | |||||||||||
| Publisher | c1990 | |||||||||||
| Year Published | 1990 | |||||||||||
| Report Number | EPA/600/J-90/356; | |||||||||||
| Stock Number | PB91-163709 | |||||||||||
| Additional Subjects | Respiratory system ; Air pollution effects(Animals) ; Air pollution effects(Humans) ; Respiration ; Dose-response relationships ; Health hazards ; Pharmacokinetics ; Tissue distribution ; Pulmonary alveoli ; Metabolism ; Reprints ; | |||||||||||
| Holdings |
|
|||||||||||
| Collation | 12p | |||||||||||
| Abstract | The development of a physiologically based pharmacokinetic model for the whole body in which inhalation, exhalation, and metabolism in respiratory tract tissues are taken into account is described. As an example of the model's use, the results of several experiments in which rats and humans were exposed to styrene were simulated; these results are discussed. The predicted results agree with the empirical data and with the modeling results of others. (Copyright (c) 1990 Princeton Scientific Publishing Co., Inc.) |