Record Display for the EPA National Library Catalog

RECORD NUMBER: 17 OF 25

OLS Field Name OLS Field Data
Main Title Method of Determining Allergenic Properties of Chemical Substances (K Metodike Opredeleniya Allergennykh Svoistv Khimicheskikh Veshchestv).
Author Alekseeva, O. G. ; Petkevich., A. I. ;
CORP Author Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1972
Report Number EPA-TR-73-265;
Stock Number PB-259 644-T
Additional Subjects Allergic diseases ; Chemical compounds ; Immunology ; Diagnostic agents ; Pharmacology ; Antigens ; Methodology ; USSR ; Translations ; Experimental data ; Guinea pigs ; Laboratory animals ; Skin(Anatomy) ; Allergens
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-259 644-T Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 8p
Abstract
A single injection into the skin of the ear of 0.02 ml of dilutions of all 6 tested allergens (from 1:500 and above) sensitized guinea pigs in 11-12 days. The allergenic activity of chemical substances can be compared by their dilution in the sensitizing injection. As the suggested method is based on the injection of large dilutions of the tested substances, it can be used to study poorly soluble products and a small amount of the injected allergen guarantees against intoxication, which weakens the development of allergy.