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RECORD NUMBER: 30 OF 120

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Main Title

DDT Metabolism: Oxidation of the Metabolite 2,2-bis(p-Chlorophenyl)ethanol by Alcohol Dehydrogenase.

Author

Suggs, Joseph E. ; Hawk, Robert E. ; Curley, August ; Boozer, Elizabeth L. ; McKinney., James D. ;

CORP Author

Food and Drug Administration, Atlanta, Ga. Atlanta Toxicology Branch. ;National Inst. of Environmental Health Sciences, Research Triangle Park, N.C.

Year Published

1970

Stock Number

PB-278 089

Additional Subjects

DDT ; Pesticides ; Insecticides ; Toxicology ; Metabolism ; Oxidation ; Chlorine organic compounds ; Alcohols ; Reprints ; Metabolites ; Toxic substances ; Ethanol/bis(chlorophenyl) ; Dehydrogenases/alcohol

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	PB-278 089	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

Abstract

A metabolite of DDT, 2,2-bis(p-chlorophenyl)ethanol, is a substrate of crystalline liver alcohol dehydrogenase. The oxidation of the substrate was detected spectrophotometrically. The p-nitrophenylhydrazone derivative of the product, 2,2-bis(p-chlorophenyl)acetaldehyde, was identified by comparing its mass spectrum and thin-layer chromatographic behavior with that of an authentic sample.

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