Record Display for the EPA National Library Catalog


Main Title Health assessment document for chloroform.
CORP Author United States. Environmental Protection Agency. Environmental Criteria and Assessment Office.; Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office,
Year Published 1985
Report Number EPA/600/8-84/004 F
Stock Number PB86-105004
OCLC Number 13024244
Subjects Chloroform--Toxicology--United States ; Air--Pollution--Physiological effect--United States ; Air--Pollution--United States--Physiological effect
Additional Subjects Chloroform--Toxicology--United States ; Air--Pollution--United States--Physiological effect ; Environmental surveys ; Public health ; Industrial hygiene ; Regulations ; Assessments ; Ecology ; Standards ; Toxicity ; Mutagens ; Epidemiology ; Occupational safety and health ; Path of pollutants
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  RA1242.C45H43 1985 Region 1 Library/Boston,MA 04/29/2016
EJED  EPA 600/8-84-004F OCSPP Chemical Library/Washington,DC 01/01/1988
EKBD  EPA-600/8-84-004F Research Triangle Park Library/RTP, NC 03/19/2004
ELBD ARCHIVE EPA 600-8-84-004F Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023 DISPERSAL
ERAD  EPA 600/8-84-004F Region 9 Library/San Francisco,CA 02/26/2013
ESAD  EPA 600-8-84-004F Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB86-105004 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1 volume (various pagings) : illustrations ; 28 cm
Chloroform is ubiquitous in the environment. The northern hemisphere background average has been determined to be approximately 14 ppt and the global average is 8 ppt. After inhalation or ingestion, highest concentrations are found in tissues with high lipid content. Chloroform has been detected in fetal liver. Chloroform would be expected to appear in human milk, because it has been found in cow's milk, cheese, and butter. Subchronic and chronic toxicity experiments with rats, mice, and dogs did not clearly establish a no-effect exposure level for systemic toxicity. Chloroform appears to have teratogenic potential when inhaled. Delayed fetal development occurred at an exposure level (30 ppm) that produced minimal maternal effects. The majority of the assays for mutagenicity and genotoxicity have yielded negative results; however, many of these results are inconclusive because of various inadequacies in the experimental protocols used.
"Final report." Distributed to depository libraries in microfiche. "September 1985." Includes bibliographical references. "EPA/600/8-84/004F."