| Main Title |
Health assessment document for chloroform. |
| CORP Author |
United States. Environmental Protection Agency. Environmental Criteria and Assessment Office.; Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
| Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, |
| Year Published |
1985 |
| Report Number |
EPA/600/8-84/004 F |
| Stock Number |
PB86-105004 |
| OCLC Number |
13024244 |
| Subjects |
Chloroform--Toxicology--United States ;
Air--Pollution--Physiological effect--United States ;
Air--Pollution--United States--Physiological effect
|
| Additional Subjects |
Chloroform--Toxicology--United States ;
Air--Pollution--United States--Physiological effect ;
Environmental surveys ;
Public health ;
Industrial hygiene ;
Regulations ;
Assessments ;
Ecology ;
Standards ;
Toxicity ;
Mutagens ;
Epidemiology ;
Occupational safety and health ;
Path of pollutants
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EHAM |
RA1242.C45H43 1985 |
|
Region 1 Library/Boston,MA |
04/29/2016 |
| EJED |
EPA 600/8-84-004F |
|
OCSPP Chemical Library/Washington,DC |
01/01/1988 |
| EKBD |
EPA-600/8-84-004F |
|
Research Triangle Park Library/RTP, NC |
03/19/2004 |
| ELBD ARCHIVE |
EPA 600-8-84-004F |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
| ERAD |
EPA 600/8-84-004F |
|
Region 9 Library/San Francisco,CA |
02/26/2013 |
| ESAD |
EPA 600-8-84-004F |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
| NTIS |
PB86-105004 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
1 volume (various pagings) : illustrations ; 28 cm |
| Abstract |
Chloroform is ubiquitous in the environment. The northern hemisphere background average has been determined to be approximately 14 ppt and the global average is 8 ppt. After inhalation or ingestion, highest concentrations are found in tissues with high lipid content. Chloroform has been detected in fetal liver. Chloroform would be expected to appear in human milk, because it has been found in cow's milk, cheese, and butter. Subchronic and chronic toxicity experiments with rats, mice, and dogs did not clearly establish a no-effect exposure level for systemic toxicity. Chloroform appears to have teratogenic potential when inhaled. Delayed fetal development occurred at an exposure level (30 ppm) that produced minimal maternal effects. The majority of the assays for mutagenicity and genotoxicity have yielded negative results; however, many of these results are inconclusive because of various inadequacies in the experimental protocols used. |
| Notes |
"Final report." Distributed to depository libraries in microfiche. "September 1985." Includes bibliographical references. "EPA/600/8-84/004F." |
