Record Display for the EPA National Library Catalog

RECORD NUMBER: 49 OF 148

Main Title Initial Submission: Letter to USEPA Reporting Results of Acute Oral Study in Rats with (Confidential Information), an Experimental Insecticide, dated 11/29/99 (Sanitized).
CORP Author ;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 2 Dec 1999
Year Published 1999
Report Number 8EHQ-1199-14605S;
Stock Number OTS-0559852
Additional Subjects Toxicity ; Insecticides ; Rats ; Laboratory animals ; Dosage ; Corn oil ; Toxic substances ; Concentrations ; Acute oral toxicity
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  OTS-0559852 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Abstract
This information concerns an experimental insecticide. The company has conducted an acute oral study in rats with the experimental insecticide. The experimental insecticide was diluted with corn oil to produce concentrations of 50, 70, 100, 140 and 200 mg/m1. These solutions were administered orally to Crj:CD(SD) rats of both sexes. Five (5) male and five (5) female rats 7-weeks of age were used per each dose level. Six dose levels were used in this study: 0 (control), 500, 700, 1000, 1400 and 2000 mg/kg/day. Following administration of the experimental insecticide, rats receiving doses of 500 mg/kg and higher were observed to have ataxic gait. For those rats receiving doses of 1400 mg/kg and higher, salivation and urinary incontinence were observed.