Record Display for the EPA National Library Catalog


Main Title Review of EPA's draft entitled "Toxicological review of acrylamide" /
Other Authors
Author Title of a Work
Swackhamer, Deborah Liebl.
Cory-Slechta, Deborah.
Publisher U.S. Environmental Protection Agency, Office of the Administrator, Science Advisory Board,
Year Published 2008
Report Number EPA-SAB-09-009
OCLC Number 785394633
Subjects Acrylamide--Toxicology
Internet Access
Description Access URL$File/EPA-SAB-09-009-unsigned.pdf
Local Library Info
Library Local Subject Local Note
EJB Letter about item dated Jan. 13, 2009 is bound in at front.
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA SAB-09-009 Headquarters Library/Washington,DC 11/16/2009
EJBD  EPA SAB-09-009 Headquarters Library/Washington,DC 11/17/2009
Collation 1 online resource (80 pages)
Title from title screen (viewed on Apr. 10, 2012). "December 19, 2008." Includes bibliographical references (pages 55-67). "EPA-SAB-09-009."
Contents Notes
"In response to a request from EPA's Office of Research and Development (ORD), the Science Advisory Board (SAB) convened an expert panel to conduct a peer review of EPA's draft Integrated Risk Information System (IRIS) assessment entitled, "Toxicologic [sic] Review of Acrylamide" (December 2007). This draft document updates EPA's current evaluation of the potential health effects of acrylamide. The SAB was asked to comment on the hazard characterization and dose-response assessment of acrylamide, including the Agency's selection of the most sensitive non-cancer health endpoint, the use of a physiologically -based toxicokinetic (PBTK) model, the derivation of a proposed oral reference dose (RfD), an inhalation reference concentration (RfC) for non-cancer endpoints, as well as the cancer descriptor, oral slope factor, and inhalation unit risk for acrylamide. The SAB Panel's report contains a number of recommendations that are aimed at making the assessment more transparent and improving the scientific bases for the conclusions presented."--Page [1].