Title from title screen (viewed on Apr. 10, 2012). "December 19, 2008." Includes bibliographical references (pages 55-67). "EPA-SAB-09-009."

"In response to a request from EPA's Office of Research and Development (ORD), the Science Advisory Board (SAB) convened an expert panel to conduct a peer review of EPA's draft Integrated Risk Information System (IRIS) assessment entitled, "Toxicologic [sic] Review of Acrylamide" (December 2007). This draft document updates EPA's current evaluation of the potential health effects of acrylamide. The SAB was asked to comment on the hazard characterization and dose-response assessment of acrylamide, including the Agency's selection of the most sensitive non-cancer health endpoint, the use of a physiologically -based toxicokinetic (PBTK) model, the derivation of a proposed oral reference dose (RfD), an inhalation reference concentration (RfC) for non-cancer endpoints, as well as the cancer descriptor, oral slope factor, and inhalation unit risk for acrylamide. The SAB Panel's report contains a number of recommendations that are aimed at making the assessment more transparent and improving the scientific bases for the conclusions presented."--Page [1].