Record Display for the EPA National Library Catalog

RECORD NUMBER: 18 OF 23

Main Title Telomerase inhibition strategies and protocols / [Texte imprimâe] :
Author Andrews, Lucy G.
Other Authors
Author Title of a Work
Tollefsbol, Trygve O.
Publisher Humana ; Quantum [distributor],
Year Published 2007
OCLC Number 494822868
ISBN 9781597455015; 1597455016; 9781588296832; 1588296830
Subjects Telomerase--Inhibitors ; ADN nuclâeotidylexotransfâerase
Internet Access
Description Access URL
Publisher description http://catdir.loc.gov/catdir/enhancements/fy0825/2007933147-d.html
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
ELBM  QP606.T44A537 2007 AWBERC Library/Cincinnati,OH 02/01/2016
Collation 1 volume (X-193 pages) ; 23 cm.
Notes
Includes bibliographical references and index.
Contents Notes
Methods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.