||Acute Dermal Toxicity Study of P-tert-butylbenzoic Acid on Rats with Attacments and Cover Letter Dated 07/23/1987.
||Hoechst Celanese Corp., Summit, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
1-dimethylethyl)benzoic Acid (98-73-7) ;
Acute Toxicity ;
Toxic substances ;
Laboratory animals ;
CAS No 98-73-7
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
Acute dermal toxicity was evaluated in 6 female SPF Wistar rats receiving single occluded applications of paratertiary butylbenzoic acid at a dose level of 2000 mg/kg of body weight. The test article was held in contact with the intact skin for a period of 24 hours. Mortality was observed within 14 days of treatment in 1 animals; the LD50 was determined to be greater than 2000 mg/kg of body weight. Clinical observations included disequilibrium problems and no signs of irritation. Weight loss was noted in some of the animals. Gross necropsy was not reported.