Record Display for the EPA National Library Catalog
RECORD NUMBER: 6 OF 11
|OLS Field Name||OLS Field Data|
|Main Title||Initial Submission: Letter from Eastman Kodak Company to Usepa Submitting Information Concerning the Prenatal Toxicity of 2-methyl-1-propanol in Rabbits after Inhalation.|
|CORP Author||Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; 2-methyl-1-propanol ; Reproduction/fertility Effects ; Teratogenicity ; Mammals ; Rabbits ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 78-83-1|
Isopropanol (78-83-1) was evaluated for developmental toxicity in Himalayan rabbits exposed by inhalation to the test substance at 0, 0.5, 2.5, and 5.0 mg/L (numbers of animals, methods and duration not reported). Cardiac septal defect defects were reported at incidences of 0.0, 0.0, 4.5, and 12.0%, respectively. The litter incidence of septal defects were reported at incidences of 0.0, 0.0, 25, and 40% , respectively. This document is a letter containing briefly summarized results.