||Analysis of Chlorinated Herbicides by High-Performance Liquid Chromatography/Mass Spectrometry.
Jones, T. L. ;
Betowski, L. D. ;
Yinon., J. ;
||Environmental Monitoring Systems Lab., Las Vegas, NV. ;Weizmann Inst. of Science, Rehovoth (Israel). ;American Chemical Society, Washington, DC.
Chemical analysis ;
Chlorine organic compounds ;
Liquid chromatography ;
Mass spectroscopy ;
||Some EPA libraries have a fiche copy filed under the call number shown.
A method that uses high performance liquid chromatography/mass spectrometry (HPLC/MS) for the analysis of chlorinated phenoxyacid herbicides is described. During method development different techniques were used to increase both the sensitivity and the specificity of thermospray HPLC/MS for chlorinated acid herbicides. These included the operation of the instrument in the negative chemical ionization (NCI) mode initiated by discharge and the use of a wire-repeller in the ion source for efficient extraction of positive ions. Single quadrupole repeller-induced and multiple quadrupole collision activated dissociation (CAD) experiments were also performed to increase the structural information of the mass spectra. The method complements the U.S. Environmental Protection Agency's gas chromatographic (GC) SW-846 Method 8151 for the determination of chlorinated acid herbicides.