| Main Title |
New Metabolite of Chlorpyrifos: Isolation and Identification. |
| Author |
Lores, Emile M. ;
Sovocool, G. Wayne ;
Harless, Robert L. ;
Wilson, Nancy K. ;
Moseman., Robert F. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, N.C. Environmental Toxicology Div. |
| Year Published |
1977 |
| Report Number |
EPA/600/J-78/023; |
| Stock Number |
PB-283 568 |
| Additional Subjects |
Pesticides ;
Toxic diseases ;
Metabolism ;
Humans ;
Poisons ;
Ingestion(Biology) ;
Liver ;
Isolation ;
Chemical analysis ;
Gas chromatography ;
Mass spectroscopy ;
Nuclear magnetic resonance ;
Phosphorus organic compounds ;
Toxicology ;
Reprints ;
Metabolites ;
Pesticide residues ;
Dursban ;
Phosphorothioates ;
Methane thiols ;
Toxic substances
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-283 568 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
A new metabolite of chlorpyrifos was discovered in a human poisoning case in which a lethal quanitity of the pesticide was ingested. The metabolite was isolated from a human liver extract. After extensive cleanup, the metabolite was subjected to various instrumental analyses such as gas chromatography, mass spectrometry, and nuclear magnetic resonance. The metabolite was identified as a compound similar to chlorpyrifos with a methylthio (-SCH3) group substituted for a chlorine on the pyridinol ring. The method of isolation and the data obtained from the instrumental analyses are presented. |
