Record Display for the EPA National Library Catalog


Main Title Use of Bioassay Methods to Evaluate Mutagenicity of Ambient Air Collected Near a Municipal Waste Combustor.
Author Watts, R. ; Fitzgerald, B. ; Heil, G. ; Garabedian, H. ; Williams, R. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher c28 Apr 89
Year Published 1989
Report Number EPA/600/J-89/446;
Stock Number PB91-109389
Additional Subjects Bioassay ; Incinerators ; Combustion products ; Waste disposal ; Reprints ; Mutagenicity tests ; Air pollution monitoring ; Solid wastes ; Risk assessment
Library Call Number Additional Info Location Last
NTIS  PB91-109389 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 6p
An ambient air sampling study was conducted around a municipal waste combustor with a primary goal being to develop procedures to evaluate the emissions of organic mutagens resulting from incomplete combustion of municipal waste. The products of incomplete combustion from incineration include complex mixtures of organics, particularly polycyclic aromatic compounds, which are present after atmospheric dilution and cooling in emissions as semi-volatile or particle bound organic compounds. Combustion emissions are generally recognized as a potential cancer risk since they contain many carcinogenic and mutagenic polycyclic aromatic hydrocarbons. Analyzing such a complex mixture for the presence of even a few selected chemicals is difficult and provides risk information on only a fraction of the chemicals present. Bioassay methods, however, may be directly applied to evaluate the mutagenic and carcinogenic activity of the complex organics from combustion emissions. The Salmonella (Ames) assay was used to determine the mutagenicity associated with particles from ambient air collected near a municipal waste combustor. Dose-response data was generated, and mutagenicity concentrations were calculated to demonstrate the utility of bioassay in assessing emissions from municipal waste combustion. (Copyright (c) 1989 Air and Water Waste Management Association.)