Record Display for the EPA National Library Catalog
RECORD NUMBER: 38 OF 213| Main Title | Combined Use of Biochemical Indicators to Assess Sublethal Pollution Effects on the Gulf Killifish ('Fundulus grandis'). | |||||||||||
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| Author | Schoor, W. P. ; Williams, D. E. ; Lech, J. J. ; | |||||||||||
| CORP Author | Environmental Research Lab., Gulf Breeze, FL. ;Medical Coll. of Wisconsin, Inc., Milwaukee. Dept. of Pharmacology and Toxicology. | |||||||||||
| Year Published | 1988 | |||||||||||
| Report Number | EPA/600/J-88/106; | |||||||||||
| Stock Number | PB88-251699 | |||||||||||
| Additional Subjects | Fishes ; Water pollution ; Toxicology ; Chico Bayou ; Oxidoreductases ; Liver ; Reprints ; Fundulus grandis ; Gulf killifish ; Water pollution effects(Animals) ; Water pollution detection ; Enzyme induction ; Cytochrome P-450 ; Anyl hydrocarbon hydroxylases ; Ethoxyresorufin O-deethylase | |||||||||||
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| Collation | 7p | |||||||||||
| Abstract | Sublethal biochemical markers were used to identify liver enzyme induction in fish from a bayou in Pensacola, Florida. Gulf killifish, Fundulus grandis, from a nonpolluted site were used in the study which included laboratory-induced fish and their various controls as well as the fish captured in the bayou. The biochemical markers tested were liver to body weight ratios, total content of cytochrome P-450, mixed function oxygenase and ethoxyresorufin-O-deethylase activities, and the specific induction of the ML4b isozyme of the cytochrome P-450 system. The findings suggest that enzyme induction occurred at a sublethal level, indicating the presence of liver enzyme inducing substances in the bayou. |