Record Display for the EPA National Library Catalog


Main Title A solid substrate immunological assay for monitoring organic environmental contaminants /
Author Lukens, Herbert R. ; Williams., Colin B.
Other Authors
Author Title of a Work
Williams, Colin B.
CORP Author IRT Corp., San Diego, Calif.;Health Effects Research Lab., Research Triangle Park, N.C. Experimental Toxicology Div.
Publisher U.S. Environmental Protection Agency, Health Effects Research Laboratory,
Year Published 1977
Report Number EPA/600/1-77/018; EPA-68-02-2202
Stock Number PB-266 357
OCLC Number 42836510
Subjects Antigen-antibody reactions ; Organic compounds--Measurement
Additional Subjects Water analysis ; Organic compounds ; Substrates ; Monitors ; Chemical analysis ; Antigen antibody reactions ; Benzimidazoles ; Recommendations ; Tables(Data) ; Immunology ; Water pollution ; Appendices ; Water pollution detection ; Benzimidazole/amino
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-77-018 Headquarters Library/Washington,DC 01/15/2014
EJBD  EPA 600-1-77-018 c.1 Headquarters Library/Washington,DC 04/24/2014
EKBD  EPA-600/1-77-018 Research Triangle Park Library/RTP, NC 06/06/2003
ELBD  EPA 600-1-77-018 AWBERC Library/Cincinnati,OH 08/26/2016
NTIS  PB-266 357 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation vii, 41 pages : illustrations ; 28 cm.
A solid substrate 'film-badge' type monitor has been developed that is capable of detecting 2-aminobenzimidazole (2-ABZI) at less than one part per million in water in less than 10 minutes. The monitor makes use of the reaction which takes place between 2-ABZI in the sample and a monolayer of its antibody that has been deposited on a thin film of indium on a glass substrate. A second approach in which the antibody is mounted on polystyrene and reaction of its antigen-binding sites with a fluorescein-labeled antigen are subject to competition with nonlabeled antigen in the sample, has been demonstrated in principle. Improvements in this alternate approach are proposed.
"EPA-600/1-77-018." EPA contract no. 68-02-2202; EPA project officer: M.F. Copeland. Includes bibliographical references (page 35).