| Main Title |
Effect of Methyl Linoleate Hydroperoxide (MLHP), A Possible Toxic Intermediate of Ozone, on Human Normal and Glucose-6-Phosphate Dehydrogenase (G-6-PD) Deficient Erythrocytes. |
| Author |
Williams, P. S. ;
Calabrese, E. J. ;
Moore, G. S. ;
|
| CORP Author |
Massachusetts Univ., Amherst. Dept. of Public Health.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1983 |
| Report Number |
EPA-R-805797; EPA/600/J-83/277; |
| Stock Number |
PB85-177855 |
| Additional Subjects |
Erythrocytes ;
Ozone ;
In vitro analysis ;
Air pollution ;
Oxidation ;
Chemical reactions ;
Public health ;
Exposure ;
Reprints ;
Chemical reaction mechanisms ;
Air pollution effects(Humans) ;
Dehydrogenase/glucose-phosphate ;
Linoleic acid/(methyl-ester)-hydroperoxy
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB85-177855 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
14p |
| Abstract |
Erythrocytes of both normal and G-6-PD deficient humans responded in a dose-dependent manner to the oxidant stress of MLHP as measured by decreases in G-6-PD activity, increases in methemoglobin (METHB) levels and decreases in reduced glutahione (GSH). The G-6-PD deficient erythrocytes displayed a markedly enhanced sensitivity to MLPH induced decreases in G-6-PD activity and METHB increases while being less sensitive than normal erythrocytes to changes in GSH levels. (Copyright (c) 1983 by Marcel Dekker, Inc.) |
