Workers are often subjected to relatively high levels of pesticide compounds when actively engaged in pest control operations or working directly with the compounds in formulating or manufacturing plants. Illnesses resulting from overexposure to pesticide chemicals do occur among such workers. Most, however, are a result of carelessness or accident. Experience has shown that if proper precautionary measures and directions are followed even the more toxic compounds can be used safely. The article discusses precautionary measures and directions.