Main Title |
A solid substrate immunological assay for monitoring organic environmental contaminants / |
Author |
Lukens, Herbert R. ;
Williams., Colin B.
|
Other Authors |
|
CORP Author |
IRT Corp., San Diego, Calif.;Health Effects Research Lab., Research Triangle Park, N.C. Experimental Toxicology Div. |
Publisher |
U.S. Environmental Protection Agency, Health Effects Research Laboratory, |
Year Published |
1977 |
Report Number |
EPA/600/1-77/018; EPA-68-02-2202 |
Stock Number |
PB-266 357 |
OCLC Number |
42836510 |
Subjects |
Antigen-antibody reactions ;
Organic compounds--Measurement
|
Additional Subjects |
Water analysis ;
Organic compounds ;
Substrates ;
Monitors ;
Chemical analysis ;
Antigen antibody reactions ;
Benzimidazoles ;
Recommendations ;
Tables(Data) ;
Immunology ;
Water pollution ;
Appendices ;
Water pollution detection ;
Benzimidazole/amino
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJBD |
EPA 600-1-77-018 |
c.1 |
Headquarters Library/Washington,DC |
04/24/2014 |
EKBD |
EPA-600/1-77-018 |
|
Research Triangle Park Library/RTP, NC |
06/06/2003 |
ELBD ARCHIVE |
EPA 600-1-77-018 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
ELBD |
EPA 600-1-77-018 |
|
AWBERC Library/Cincinnati,OH |
08/26/2016 |
NTIS |
PB-266 357 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
vii, 41 pages : illustrations ; 28 cm. |
Abstract |
A solid substrate 'film-badge' type monitor has been developed that is capable of detecting 2-aminobenzimidazole (2-ABZI) at less than one part per million in water in less than 10 minutes. The monitor makes use of the reaction which takes place between 2-ABZI in the sample and a monolayer of its antibody that has been deposited on a thin film of indium on a glass substrate. A second approach in which the antibody is mounted on polystyrene and reaction of its antigen-binding sites with a fluorescein-labeled antigen are subject to competition with nonlabeled antigen in the sample, has been demonstrated in principle. Improvements in this alternate approach are proposed. |
Notes |
"EPA-600/1-77-018." EPA contract no. 68-02-2202; EPA project officer: M.F. Copeland. Includes bibliographical references (page 35). |