Record Display for the EPA National Library Catalog

RECORD NUMBER: 2 OF 9

Main Title Factor Interactions and Aquatic Toxicity Testing.
Author Voyer, R. A. ; Heltshe, J. F. ;
CORP Author Environmental Research Lab., Narragansett, RI.
Year Published 1984
Report Number EPA-600/J-84-045 ;CONTRIB-348;
Stock Number PB84-220920
Additional Subjects Metals ; Toxicity ; Aquatic animals ; Water pollution ; Mathematical models ; Exposure ; Bioassay ; Tests ; Responses ; Experimental design ; Reprints ; Heavy metals
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NTIS  PB84-220920 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract
Hypothesizing that experimental variables constituting an exposure situation act independently when in combination, the authors have reviewed two published data sets dealing with effects of metal mixtures on aquatic animals in order to assess the potential practical significance of factor interactions and their implication to the design of aquatic toxicity tests. Both data sets were re-analyzed using three predictive models. The relative effectiveness of each model in predicting joint effects of independent test variables was evaluated in terms of calculated mean-square error and goodness-of-fit values, as well as by how well predicted treatment effects compared with responses observed by original investigators. A sequential testing protocol is presented which would permit an evaluation of the existence of factor interactions.