||Approach for Development of Structure-Biodegradation Relationships of Organic Chemicals.
Niemi, G. J. ;
Veith, G. D. ;
||Environmental Research Lab.-Duluth, MN. ;Minnesota Univ.-Duluth.
Organic compounds ;
Aquatic microbiology ;
Water chemistry ;
Chemical composition ;
Organic chemistry ;
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The study presents a strategy for evaluation of biodegradability of chemicals which involves a combination of structure-biodegradation relationships (SBR) and laboratory testing arranged in a four-tier hierarchy. The first tier involves a search of a data base on biodegradation information. Each subsequent tier consists of a query of potential SBR for the chemical or an experimental laboratory test of the chemical using a tier-specific procedure. The approach satisfies the critical need to develop a systematic reference data base on biodegradation endpoints for existing and new chemicals, incorporates the metabolites of biodegradation into the process, and provides an economical means to evaluate chemical biodegradation.