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Main Title Role of Fungal Ligninolytic Enzymes in Pollutant Degradation.
Author Hammel, K. E. ; Tardone, P. J. ; Price, L. A. ;
CORP Author State Univ. of New York Coll. of Environmental Science and Forestry, Syracuse.;Environmental Protection Agency, Cincinnati, OH. Risk Reduction Engineering Lab.;Air and Waste Management Association, Pittsburgh, PA.
Publisher Feb 89
Year Published 1989
Report Number EPA-R-813530; EPA/600/A-93/115;
Stock Number PB93-194223
Additional Subjects Waste treatment ; Hazardous materials ; Biological treatment ; Fungi ; Biodeterioration ; Enzymes ; Lignin ; Oxidation ; Depolymerization ; Aromatic compounds ; Aromatic polycyclic hydrocarbons ; Biochemistry ; Microorganisms ; Reprints ; Phanerochaete chrysosporium
Library Call Number Additional Info Location Last
NTIS  PB93-194223 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
The ligninolytic fungi that cause white rot of wood have recently become the object of increasing attention from hazardous waste management specialists. The metabolic pathways that they employ for ligninolysis appear to have unusual xenobiotic capabilities, and there is some preliminary evidence that their extracellular lignin peroxidases, which normally catalyze the depolymerization of lignin, could bring about the initial oxidation of certain aromatic pollutants in vivo. However, it remains to be demonstrated that high levels of lignin peroxidase activity will necessarily lead to improved rates of pollutant degradation, or indeed that these enzymes are actually involved in any of the fungal xenobiotic oxidations that have been observed. To address these questions, the authors have begun a study of anthracene metabolism in the lignin degrader Phanerochaete chrysosporium: this simple model pollutant is quantitatively oxidized to anthraquinone by purified lignin peroxidases, is at least to some extent oxidized to the same quinone by whole fungal cultures, and is also mineralized at appreciable rates in vivo. The results point to a role for lignin peroxidases in organopollutant degradation by Phanerochaete, but more work is required to elucidate the pathways involved.