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RECORD NUMBER: 2 OF 12

OLS Field Name OLS Field Data
Main Title Evaluation of 10 Chemicals for Aneuploidy Induction in the Hexaploid Wheat Assay.
Author Sandhu, S. S. ; Dhesi, J. S. ; Gill, B. S. ; Svendsgaard, D. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;North Carolina Central Univ., Durham. Dept. of Biology. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-91/268;
Stock Number PB92-113307
Additional Subjects Aneuploidy ; Mutagens ; Wheat ; Mutagenicity tests ; Mitotic spindle apparatus ; Tables(Data) ; Bioassay ; Reprints ; Seedlings
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB92-113307 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 02/24/1992
Collation 7p
Abstract
The study was a part of an international project sponsored by the Commission of the European Communities to evaluate the utility of certain bioassays including hexaploid wheat assay to identify potential aneugens. Ten suspect spindle poisons, i.e. colchicine (COL), cadmium chloride (CdCl2), chloral hydrate (CH), diazepam (DIZ), econazole (EZ), hydroquinone (HQ), pyrimethamine (PY), thiabendazole (TB), thimerosal (TM), and vinblastin sulphate (VBL) were tested for their ability to induce green and/or white leaf sectors as indicators of loss or gain of a chromosome respectively, in Neatby's strain of Chinese Spring wheat (2n = 6x=42). All the chemicals tested in the study, with the exception of CH and HQ yielded positive response.