Record Display for the EPA National Library Catalog

RECORD NUMBER: 4 OF 11

Main Title Effect of Ozone Exposure upon Hepatic and Serum Ascorbic Acid Levels in Male Sprague-Dawley Rats.
Author Calabrese, E. J. ; Moore, G. S. ; Weeks, B. L. ; Stoddard, A. ;
CORP Author Massachusetts Univ., Amherst. Dept. of Public Health.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA-R-805797; EPA/600/J-83/275;
Stock Number PB85-173219
Additional Subjects Ozone ; Ascorbic acid ; Toxicology ; Exposure ; Bioassay ; Rats ; Mice ; Laboratory animals ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB85-173219 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 18p
Abstract
Exposure of male Sprague-Dawley rats to 0.3 ppm ozone for 3 hours resulted in a time-delayed increase in serum and hepatic reduced ascorbic acid levels as compared to controls (0.0 ppm O3) which exhibited an immediate increase in hepatic and serum ascorbic levels. After 24 hours ascorbic acid levels in both groups approached but did not return to pre-exposure values. The immediate increase in ascorbic acid levels in the controls was unexpected and may reflect previously unrecognized chamber and/or handling effects. (Copyright (c) 1983 by Marcel Dekker, Inc.)