Record Display for the EPA National Library CatalogRECORD NUMBER: 2 OF 20
|Main Title||Behavioral Development Following Daily Episodes of Mother-Infant Separation in the Rat.|
|Author||Stanton, M. E. ; Crofton, K. M. ; Lau, C. ;|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC.|
|Additional Subjects||Toxicology ; Behavior ; Laboratory animal science ; Maternal deprivation ; Rats ; Mothers ; Infants ; Neuropsychological tests ; Reprints ;|
Sprague-Dawley rat pups were either maternally deprived in warm incubators for 6 hours each day or left alone with their dams, and then tested on a range of endpoints commonly used in developmental neurotoxicity. These included motor activity, olfactory learning and retention, T-maze delayed alternation, acoustic startle response, and auditory thresholds. Interrupting the mother-infant interaction for 6 hours/day had little or no effect by itself on growth and behavioral development.