Record Display for the EPA National Library Catalog


Main Title Antimutagenicity Profiles of Synthetic and Natural Antimutagens.
Author Waters, M. D. ; Brady, A. L. ; Stack, H. F. ; Brockman, H. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC. ;Illinois State Univ., Normal. Dept. of Biological Sciences.
Publisher cJun 93
Year Published 1993
Report Number EPA/600/J-94/335;
Stock Number PB94-202090
Additional Subjects Toxicology ; Antimutagenic agents ; Anticarcinogenic agents ; Dosage ; Experimental data ; Mutagenesis ; Carcinogenesis ; Aflatoxin B1 ; Benzo(a)pyrene ; Butylated hydroxyanisole ; Butylated hydroxytoluene ; Glutathione ; Vitamin A ; Reprints ;
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
NTIS  PB94-202090 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 50p
The concept of activity profile listings and plots, already applied successfully to the display of mutagenicity data, has been modified for application to antimutagenicity data. The activity profiles are bar graphs that have been organized in two general ways: for antimutagens that have been tested in combination with a given mutagen and for mutagens that have been tested in combination with a given antimutagen. The report examines synthetic as well as natural antimutagens and compares their activity against known mutagens. It is not clear at the present time whether the inhibition of carcinogen-induced mutation is a good indicator of anticarcinogenic properties, and further research is needed. Nevertheless, the activity profiles are useful for the assessment of the available antimutagenesis data by providing rapid visualization of dose information and experimental results.