Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Complement Receptor Positive Spleen Cells in Microwave (2450-MHz)-Irradiated Mice.
Author Smialowicz, R. J. ; Brugnolotti, P. L. ; Riddle, M. M. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Experimental Biology Div.
Year Published 1981
Report Number EPA-600/J-80-166;
Stock Number PB82-127481
Additional Subjects Microwaves ; Radiation effects ; Dose rate ; Mice ; Exposure ; Laboratory animals ; Spleen ; Cells(Biology) ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB82-127481 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 7p
Male CBA/J mice were exposed under far-field conditions in a temperature and humidity controlled environment to 2450-MHz (CW) microwaves. Mice were exposed once for 30 minutes at a power density of 15, 20, 30, or 40 mW/sq. mc. The whole-body-averaged dose rate was approximately 0.7 mW/g per mW/sq. cm. Six days after irradiation, the percentage of complement-receptor-positive (CR+) spleen cells was determined. No difference was observed in the percentage of CR+ spleen cells of young adult (10-12 week-old) mice exposed at any of the power densities as compared with sham-irradiated controls. However, a significant (P<.05) increase was observed in the percentage of CR+ cells from 16-week old mice exposed at 40 mW/sq. cm. This increase in CR+ cells was accompanied by a significant (P<.05) decrease in the number of nucleated cells in the spleens of these mice. This change in CR+ and nucleated spleen cells was not consistently produced. The available data indicate that the age and strain of the mouse, the microwave exposure characteristics, and the environmental conditions may all be sources of variation that affect the CR+ end point.