Record Display for the EPA National Library Catalog


Main Title Multiresidue Procedure for Halo- and Nitrophenols. Measurement of Exposure to Biodegradable Pesticides Yielding these Compounds as Metabolites.
Author Shafik, Talaat M. ; Sullivan, Hazel C. ; Enos., Henry R. ;
CORP Author Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
Year Published 1973
Stock Number PB-276 901, PB-276 897
Additional Subjects Pesticides ; Chemical analysis ; Nitrophenols ; Phenols ; Halogen organic compounds ; Metabolism ; Laboratory animals ; Urine ; Hydrolysis ; Extraction ; Gas chromatography ; Electron capture ; Concentration(Composition) ; Biodeterioration ; Reprints ; Electron capture gas chromatography
Library Call Number Additional Info Location Last
NTIS  PB-276 901 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 4p
The urinary level of phenolic compounds may be the key for establishing an index of exposure to pesticides containing this moiety as an easily hyrolyzed or metabolized portion of the molecule. A method has been developed for quantitating ten halo- and nitrophenols in rat urine which could result from exposure to and subsequent metabolism and excretion of a broad spectrum of pesticides. The procedure involves acid hydrolysis, extraction, derivatization, silica gel chromatography, and electron-capture gas chromatography. Male rats fed pesticidal compounds containing halo- and nitrophenol moieties at levels varying from factors of 0.00001 to 0.01 of the LD50 were used to establish the usefulness of this procedure for determining the extent of exposure to the biodegradable pesticides.
found in PB-276 897 titled: Journal articles on pesticide chemical analysis. Group 5.