Main Title |
Chlorinated Organic By-Products of the Reaction of N-Chloropiperidine with Stomach Fluid from Laboratory Animals. |
Author |
Scully, F. E. ;
Mazina, K. E. ;
Ringhand, H. P. ;
Chess, E. K. ;
|
CORP Author |
Old Dominion Univ., Norfolk, VA. Dept. of Chemical Sciences. ;Battelle Pacific Northwest Labs., Richland, WA.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1987 |
Report Number |
EPA-R-813092; EPA/600/D-87/230; |
Stock Number |
PB87-212650 |
Additional Subjects |
Chlorine organic compounds ;
Toxicology ;
Water treatment ;
Potable water ;
Chlorides ;
Piperidines ;
Gastric juice ;
Rats ;
Laboratory animals ;
Chemical reactions ;
pH ;
Chlorination ;
Piperidine/chloro
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB87-212650 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
25p |
Abstract |
When (36)Cl-N-chloropiperidine (NCP) (300 mg/L as Cl2) was mixed with stomach fluid from laboratory rats (fasted either 24 or 48 hr) and incubated in the dark for 30 min at 37 deg C and at higher pH values, approximately one-third was reduced to chloride and between 7% and 63% of the radiolabel was found to chromatograph in a manner distinctly different from (36)Cl-chloride or (36)Cl-NCP. This new fraction is referred to as the (36)Cl-chloroorganic fraction. The remainder of the radiolabel was associated with (36)Cl-NCP. |