| Main Title |
Chloroform Induction of Ornithine Decarboxylase Activity in Rats. |
| Author |
Savage, Jr., Russell E. ;
Westrich, Carol ;
Guion, Charles ;
Pereira, Michael A. ;
|
| CORP Author |
Health Effects Research Lab., Cincinnati, OH. |
| Year Published |
1982 |
| Report Number |
EPA-600/J-81-375; |
| Stock Number |
PB83-189050 |
| Additional Subjects |
Chloroform ;
Toxicology ;
Carcinogens ;
Malignant neoplasms ;
Reprints ;
Carcinogenesis ;
Cancer ;
Ornithine decarboxylase
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-189050 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Chloroform is a drinking water contaminant that has been demonstrated to be carcinogenic to mice and rats resulting in an increased incidence of liver and kidney tumors, respectively. The mechanism of chloroform carcinogenicity might be by tumor initiation and/or promotion. Since induction of ornithine decarboxylase (ODC) activity has been proposed as a molecular marker for tumor promoters, the authors have investigated the effect of chloroform on ODC activity in rats. |
