Record Display for the EPA National Library Catalog
RECORD NUMBER: 23 OF 24| Main Title | Toxicology of Organic Drinking Water Contaminants: Trichloromethane, Bromodichloromethane, Dibromochloromethane and Tribromomethane. | |||||||||||
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| Author | Munson, Albert E. ; Sain, Larry E. ; Sanders, Virginia M. ; Kauffmann, Bernadine M. ; White, Kimber L. ; | |||||||||||
| CORP Author | Virginia Commonwealth Univ., Richmond.;Health Effects Research Lab., Research Triangle Park, NC. | |||||||||||
| Year Published | 1982 | |||||||||||
| Report Number | EPA-R-804701; EPA-600/J-81-369; | |||||||||||
| Stock Number | PB83-187872 | |||||||||||
| Additional Subjects | Toxicology ; Potable water ; Halomethanes ; Bioassay ; Contaminants ; Reprints ; Drinking water ; Water pollution effects(Animals) | |||||||||||
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| Collation | 12p | |||||||||||
| Abstract | This study evaluated the subchronic toxicity of selected halomethanes which are drinking water contaminants. The compounds studied were trichloromethane, bromodichloromethane, dibromochloromethane and tribromomethane. Subchronic 14-day gavage studies were performed with the use of doses encompassing one-tenth the LD50 for the compounds. A 90-day gavage study of one of the compounds, trichloromethane, was also done. Parameters observed included body and organ weights, histopathology, hematology, clinical chemistries, and hepatic microsomal enzyme activities. |