| Main Title |
Transport of Conjugates of Toxicants by Blood Proteins. |
| Author |
Shah, P. V. ;
Helling, D. J. ;
Maliwal, B. P. ;
Guthrie, F. E. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;North Carolina State Univ. at Raleigh. ;Northrop Services, Research Triangle Park, NC. ;Maryland Univ., Baltimore. School of Medicine. |
| Year Published |
1985 |
| Report Number |
EPA/600/J-85/133; |
| Stock Number |
PB86-102357 |
| Additional Subjects |
Toxicology ;
Blood ;
Proteins ;
In vitro analysis ;
In vivo analysis ;
Binding ;
Naphthal ;
Reprints ;
Conjugates
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-102357 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
Binding of naphthol and its glucoside and glucuronide conjugates by blood proteins was studied in vitro and in vivo. Binding was found to primarily to the albumin fraction of human blood and the binding constants were moderate to low. Both in vivo (mice) and in vitro (human) experiments suggest that a substantial portion of naphthol and two conjugates are transported in bound form to the site of elimination. |
