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RECORD NUMBER: 18 OF 48

Main Title Five-Year Follow-up Study of Children with Low-to-Moderate Lead Absorption: Electrophysiological Evaluation.
Author Otto, D. ; Robinson, G. ; Baumann, S. ; Schroeder, S. ; Mushak, P. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;North Carolina Univ. at Chapel Hill.
Year Published 1985
Report Number EPA/600/J-85/266;
Stock Number PB86-158565
Additional Subjects Toxicology ; Lead(Metal) ; Children ; Exposure ; Blood chemical analysis ; Electrophysiology ; Reprints ; Heavy metals ; Evoked responses
Holdings
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Status
NTIS  PB86-158565 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 21p
Abstract
Forty-nine children aged 6 to 12 years were evaluated for residual effects of lead exposure using psychometric, electrophysiological, and medical tests five years after initial assessment. The original range of blood lead (PbB) levels was 6-59 micrograms/dl; the current range was 6-30 micrograms/dl. A linear relationship between PbB and slow brain wave voltage during sensory conditioning was observed at initial evaluation (Otto, et al., 1981) and at two-year follow-up (Otto, et al. 1982). No significant relationship between PbB and slow wave voltage during passive conditioning was found at five-year follow-up, although a linear increase in slow wave negativity relative to current PbB level during active conditioning was suggested by exploratory analyses. Another exploratory analysis revealed a significant linear relationship between original PbB level and the latency of waves III and V of the brainstem auditory evoked potential.