||Organ and species specificity in chemical carcinogenesis /
Langenbach, Robert ;
Nesnow, Stephen ;
Rice, Jerry M.
||Health Effects Research Lab., Research Triangle Park, NC. ;National Cancer Inst., Frederick, MD. Lab. of Comparative Carcinogenesis.
|| U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
Chemical carcinogenesis--Congresses ;
Organ Specificity ;
Species Specificity ;
Organ Specificity--congresses ;
In vitro analysis ;
Deoxyribonucleic acids ;
Laboratory animals ;
Malignant neoplasms ;
Organ specificity ;
||Some EPA libraries have a fiche copy filed under the call number shown.
||699 pages : illustrations ; 26 cm.
The focus of the Symposium and this volume is the relative susceptibility of specific animal species strains and organs to various carcinogens. For the first time, investigators in chemical carcinogenesis are able to pool their discoveries in this area. Once analyzed, this data could substantially contribute to man's understanding of potential carcinogens and their human health effects and increase the possibility of cancer prevention. The thirty-five papers fall into six general areas: comparative effects of chemical carcinogens, promoting agents, metabolism as a determinant of organ specificity, species and organ specificity as studied by in vitro techniques, DNA damage and repair, and risk extrapolation. Discussion generated by the presentations are also included.
"Proceedings of a Symposium on Organ and Species Specificity in Chemical Carcinogenesis, held during March 1981, in Raleigh, North Carolina"--Title page verso. Includes bibliographical references and indexes. "June 1983." Microfiche.