This manual provides the pesticide chemist with methodology useful in determining human exposure to pesticides and related industrial chemicals. Methods are also presented for measuring the extent of environmental contamination with these compounds. This manual has been compiled and produced in an effort to promote general acceptance and adoption of uniform chemical methodology of utmost reproducibility and accuracy and to ensure that analytical results can be correlated and directly compared between laboratories. Methods contained in this manual have generally been developed and/or evaluated by this laboratory within the Environmental Toxicology Division. The analytical methodology compiled herein consists of both multiresidue and specific residue procedures. Included also, are miscellaneous topics treating a number of important activities such as the cleaning of laboratory glassware, the preparation of analytical reference standards, and the calibration and maintenance of the gas chromatograph. Several of the methods have been subjected to collaborative studies and have thereby been proved to produce acceptable interlaboratory precision and accuracy. These methods are designated by stars placed at the left of the title in the Table of Contents. Other methods presented are thought to be acceptable but have not been validated by formal interlaboratory collaboration.

Cover title: Manual of analytical methods for the analysis of pesticides in humans and environmental samples. Revisions by the Association of Official Analytical Chemists, Joseph Sherma, Morton Beroza. "June 1980." "EPA-600/8-80-038." "Contract no. 63-02-2474." Includes bibliographical references and index.