Record Display for the EPA National Library Catalog


Main Title Use of aquatic lethality tests to estimate safe toxicant concentrations for initial ecolological risk assessments /
Author Holcombe, G. W. ; Phipps, F. L. ; Veith, G. D.
Other Authors
Author Title of a Work
Phipps, G. L.
Veith, G. D.
CORP Author Environmental Research Lab., Duluth, MN.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Environmental Research Laboratory,
Year Published 1989
Report Number EPA/600/D-89/175; ERL-DUL-2322; ISBN-0-8031-1180-0
Stock Number PB90-116104
Subjects Marine pollution
Additional Subjects Aquatic biology ; Minnows ; Lethal dosage ; Extrapolation ; Comparison ; Ecology ; Reprints ; Water pollution effects(Animals) ; Toxic substances ; Risk assessment ; Environmental monitoring
Library Call Number Additional Info Location Last
NTIS  PB90-116104 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 22 pages : illustrations ; 28 cm
The article presents an approach which allows a body of comparative toxicity data to be used as initial ecological risk assessments in order to extrapolate from an acute test with an indicator species an estimate of the no-effect concentration in the environment. The fathead minnow (Pimephales promelas) acute value was selected as the reference value since this ecotoxicity endpoint has the largest data base for comparative toxicity comparisons. Comparative toxicity endpoints for fish and invertebrates were collected from various sources. When data for all ecotoxicity endpoints are plotted for all chemicals, this plot can be analyzed statistically using regression analysis to calculate an equation defining the upper 95 percentile prediction limit. The upper 95% prediction limit uses the reference test (fathead 96-h acute value) to calculate a concentration that would be safe for 95% of the species and chemicals, assuming that enough comparative toxicological data (especially chronic end-points) are included in the data set. (Copyright (c) by American Society for Testing and Materials, 1988.)
"EPA/600/D-89/175." Includes bibliographical references. "Published in: Aquatic Toxicology and Environmental Fate: Eleventh Volume, ASTM STP 1007, G.W. Suter II and M.A. Lewis, Eds. American Society for Testing and Materials, Philadelphia, PA, 1989, pp. 442-458." Microfiche.