The first sulfonylurea herbicide, chlorsulfuron was introduced in 1982. Members of this new herbicide class are known for their high toxicity toward plant growth, low application rate, extremely low toxicity to humans and other animals, and phytotoxicity reported due to the inhibition of a single enzyme (acetolactate synthase). There are some anecdotal claims from certain regions of the United States that drifting sulfonylureas have caused crop losses by disrupting normal reproductive processes. The authors have used fruit yield on cherry trees as a model system to evaluate the influence of sulfonylureas on plant reproduction.